Found 77 matching trials
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer PHASE3 The purpose of this study is to evaluate the effectiveness of niraparib in ...
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Location
Urology Centers Of Alabama
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Niraparib Maintenance Treatment in mCRC With a Partial o Complete Response After Oxaliplatin-based Induction Therapy PHASE2 Colorectal Cancer ranks third among the most frequent malignancies represen...
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Multiple Locations
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Niraparib in Combination With Trastuzumab in Metastatic HER2+ Breast Cancer PHASE1 The human epidermal growth factor receptor 2 (HER2) regulates cell growth a...
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Location
University of Alabama at Birmingham
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Trial on NIraparib-TSR-042 (Dostarlimab) vs Physician's Choice CHEmotherapy in Recurrent, Ovarian, Fallopian Tube or Primary Peritoneal Cancer Patients Not Candidate for Platinum Retreatment PHASE3 Randomized phase 3 trial evaluating niraparib plus dostarlimab vs chemother...
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Azienda Ospedaliera Spedali Civili
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Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma EARLY_PHASE1 This is an open-label, multi-center Phase 0 study with an expansion phase t...
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Location
St. Joseph's Hospital and Medical Center
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Niraparib Efficacy in Patient With Unresectable Mesothelioma PHASE2 Multicentre, 2 arm, open-label UK randomised phase II trial to determine th...
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University Hospital Southampton, Southampton General Hospital
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A Trial of Niraparib in Platinum-Sensitive Castration-Resistant Prostate Cancer With DNA Repair Defects PHASE2 This study is designed to evaluate the initial safety and effectiveness of ...
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Abramson Cancer Center of the University of Pennsylvania
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A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma PHASE3 The goal of this Phase 3 clinical trial is to compare the efficacy of nirap...
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Location
University of Alabama at Birmingham
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A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer PHASE2 The purpose of this study is to: a) establish the recommended phase 2 dose ...
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Location
Urological Associates of Southern Arizona, P.C.
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Recurrent Ovarian CarcinoSarcoma Anti-pd-1 Niraparib PHASE2 Carcinosarcomas (CS) (malignant mixed Müllerian tumors) are highly aggressi...
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